上海交通大学生命科学技术学院于明课题组招聘博士后一名。应聘人应在近期获得博士学位，熟悉分子生物学、动物细胞培养和小鼠遗传学的基本操作。应聘人在入职之后可以依照学校的政策逐级晋升。年薪不少于24.2万；如果入选各级博士后激励计划、还会增加。其它待遇依照学校规定。本课题组的研究方向为血细胞发育和癌症的转录调控，主要利用基因组学、蛋白组学、小鼠遗传学和生物信息技术来阐明转录因子在生理条件下调控血细胞的发育的分子机理以及相关的转录失调诱发癌症的分子机理。

联系人：于明，邮箱：mingyu@sjtu.edu.cn

参考文献

1. Yu, M., Yang, W., Ni, T., Tang, Z., Nakadai, T., Zhu, J., and Roeder, R.G. (2015) RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II. Science 350, 1383-1386.

2. Yu, M., Mazor, T., Huang, H., Huang, H. T., Kathrein, K. L., Woo, A. J., Chouinard, C. R., Labadorf, A., Akie, T. E., Moran, T. B., Xie, H., Zacharek, S., Taniuchi, I., Roeder, R. G., Kim, C. F., Zon, L. I., Fraenkel, E., and Cantor, A. B. (2012) Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors, Mol Cell 45, 330-343.

3. Yu, M., Riva, L., Xie, H., Schindler, Y., Moran, T. B., Cheng, Y., Yu, D., Hardison, R., Weiss, M. J., Orkin, S. H., Bernstein, B. E., Fraenkel, E., and Cantor, A. B. (2009) Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis, Mol Cell 36, 682-695.

4. Yu, M., Wan, M., Zhang, J., Wu, J., Khatri, R., and Chi, T. (2008) Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development, Proc Natl Acad Sci U S A 105, 3873-3878.